Unmatched Evidence

Cook Medical

Two decades of evidence, including over 30 peer-reviewed studies and meta-analyses, confirm that minocycline and rifampin (M+R) catheters are an effective tool to provide broad-spectrum protection against gram-positive, gram-negative, and some fungal infections in both short- and long-term use.

Process Plus Antimicrobial Catheter Technology

CLABSI rate
A comparative study

Process with Ch-SS+ (AGB+) Process with M+R
2.1 1
1.4 1

Infections per 1,000 Catheter Days

Ch-SS+ ARROWg+ard® Blue Plus® M+R Cook Spectrum®

Microorganisms isolated from patients with CLABSI from central venous catheters placed in the surgical ICU 1

Gram Positive Gram Negative Fungal
1.03
.76
.52
.25
.52
.32

Infections per 1,000 Catheter Days

Ch-SS+ ARROWg+ard® Blue Plus® M+R Cook Spectrum®
References – Unmatched Evidence
  1. Bonne S, Mazuski J, Sona C, et al. Effectiveness of minocycline and rifampin vs chlorhexidine and silver sulfadiazine-impregnated central venous catheters in preventing central line-associated bloodstream infection in a high-volume academic intensive care unit: a before and after trial. J Am Coll Surg. 2015;221(3):739-747.